Boston Leadership Institute

2013 Session 1 wiki

2013 Session 2 wiki

2104 Session 1 wiki


Basic Genetics

DNA structure

Griffeth and Avery experiments (and other material on discovery of DNA)
Hershey-Chase Experiment
Watson, Crick, Chargraff, Franklin, and Wilkins contributions
DNA Replication does not fully work but good animations on DNA structure and lagging strand
Another DNA Replication animation
Replication video
Another Replication animation
Meselson and Stahl experiment
Protein Synthesis
Transcription
Regulated transcription
Translation
Video of Transcription and Translation
Another on Protein Synthesis
tryptophan repressor
lac operon
Telomere Replication
DNA Interactive
DNA from the Beginning
Learn Genetics

Investigation of epigenetics



Medical Genetics:

Genetics Home reference

NIH Genes and diseases
Genome.org scroll down for links on diseases and genetic counseling
Human Genome
Genetic disorders with different ethnic group frequencies
National Genetic Counselor Organization
Mayo Clinic Disease Index
Family Doctor.org
Medline Plus
Your Genes, Your Health


Genetic Engineering

GMO Foods

Scientific American Genetic Engineering Articles
UNL AgBiosafety
Genetic Engineering Chestnut trees
GE eHow video channel
Yale lecture series on biomedical engineering (#4)
YouTube excerpt of MIT GE lecture
A Hippy Vegan Yoga Instructor on GMOs


Bioinformatics

Bioinformatics tools

Sanger Method tutorial video
Bioinformatics Kosinski exercises
Bioinformatics ecercises pdf
data files

Engineering Principles

Video on design and synthetic biology by James King (Hastings Center)

Explanation of the Engineering Design Process
Design criteria
Teacher's Domain video and essay on the Engineering Design Process
A comparison of Science, Engineering and Technology


Synthetic Biology

Hacking genomes and synthetic biology (1 hour talk)

Decoding Synthetic Biology (YouTube)
What is synthetic biology?( pdf)
A Life of Its Own ( pdf)
Our Synthetic Futures
Synthetic Biology: Tools to Design, Build, and Optimize Cellular Processes
Synthetic Biology Explained on YouTube
Synthetic Kingdom on YouTube
Decoding Synthetic Biology (YouTube)
BioBricks Foundation
Registry of Standard Biological Parts
iGEM
iGEM High School Division
By controlling living systems synthetic biology will change the world
SynBio and de-extinction TED talk
Handmade Biology
Why Synthetic Biology Is the Field of the Future
Synthetic Biology: An Emerging Engineering Discipline
Factory of Life
Tom Knight (youTube)
Drew Endy, Viruses and Microbes (YouTube)
Engineering a new business

iGEM student book


Synbio and logic circuits

Mining logic gates in prokaryotic transcriptional regulation networks

Bacteria that can take pictures and invade tumors
Bacterial transistor devices
Harnessing nature’s toolbox regulatory elements for synthetic biology
Advancing the Design of Diverse Genetic Systems
Engineering gene circuits
Exploring and exploiting genetic modularity through the design of novel biological networks
Biological Circuits for Synthetic BiologySurvey of molecular logic gatesDNAzymesmolecular logic gates

Synbio and computers/transistors (see also logic gates)
Turning bacteria into computers
Article on using logic gate in bacterial computing
Scientists create transistor-like biological device
Tiny DNA Switches Aim To Revolutionize 'Cellular' Computing
How to turn living cells into computers
Amplifying Genetic Logic Gates
DNA Inside Cells Can Serve As Rewritable Data Storage
Totally RAD: Bioengineers create rewritable digital data storage in DNA
Tiny DNA Switches Aim To Revolutionize 'Cellular' Computing
This new discovery will finally allow us to build biological computers
Transcriptors & Boolean Integrase Logic (BIL) gates, explained (YouTube)
Recombinatorial logic
Amplifying Genetic Logic Gates



Synbio and bacterial photographs

Bacterial photography TED talk

Jaff Tabor paper on bacterial photos with multiple frequencies
A Sensing Array of Radically Couples Genetic Biopixels
Mulitichromatic Control of Gene Expression in E. coli



Synbio and quorum sensing

Quorum sensing: How bacteria talk TED talk.

Quorum sensing and synbio
Quorum sensing paper
Bacterial Quorum Sensing Signals Circuits and Implications for Biofilms and Disease
Applications of quorum sensing to biotechnology


Synbio and synthetic fuels

Jay D Keasling: Synthetic Biology Towards Biofuels (YouTube)

Synthetic biology approaches to biofuel production
New Synthetic Biology Technique Boosts Microbial Production of Diesel Fuel
Petroleum replicas
Can Synthetic Biology Produce Cheaper Biofuel? Should It?
Synthetic Biology and the Technicity of Biofuels
Chemical synthesis using synthetic biology
Toward a Synthetic Chloroplast



Synbio and therapeutics

The Clinical Potential of Synthetic Biology

"Synthetic Biology" Yields Bacteria That Take Pictures and Target Tumors
Scientists engineer suicide bacterial bombers
Beta-lactams and bacterial pharmacology
Invasion of Cancer Cells by Engineered Bacteria



Synbio and minimal cells/rewriting the genome/chassis design

Rewriting the genome

Synthetic cells and genomes PPT
Craig Venter unveils synthetic life Ted talk
Genome wide codon replacement
Hacking the Genome
Evolution Machine (MAGE)


Synbio and biosensors

SYNTHETIC BIOLOGY AND THE ART OF BIOSENSOR DESIGN



Ethics and Safety

Ethical Issues in Synthetic Biology

The Promise and Perils of Synthetic Biology
"Four suggestions for addressing public concern regarding synthetic biology"
"Mapping the moral boundaries of biological engineering"
"Synthetic biology: enormous possibility, exaggerated perils"
Responsible conduct for synthetic biology
Synbio and DARPA
Synbio and war
Synbio and DIY genetic engineering
Biological risk assessment
Synthetic Life?
SynBio What Challenges?
New genetic recipes: Cooking up trouble?
Security issues
SynBERC Guidelines
Screening out terrorists
Odds flu strain escapes
Carefully precautionary about synbio
Links about man-made mutant flu (H5N1)


Interesting iGEM projects

Mini iGEMs

2012 Penn bacterial therapeutics (cancer)
2012 Colorodo quorum stopping
2009 Calgary quorum sensing
2008 Kyoto Raise the Titanic (bacterial gas)
2012 Groningen bacterial food preservation (also kill switch)
2011 St. Andrews kill switch
2009 Cambridge E chromi/environmental sensor
2011 Penn State radiation sensor
2010 Harvard iGarden




Other resources

Many great biology animations

More great biology animations
Many great A&P animations
Harvard HHMI outreach (animations)
AP Bio animations
Bozeman Science web casts (explaining A&P systems and AP Bio labs)
Rediscovering Biology
BioCoach
AP Bio virtual labs
Biology Glossary
Another biology glossary
Suffixes and Prefixes